Estrogen Cream for Vaginal Dryness: A Comprehensive Guide Women who have gone through menopause or have had their ovaries removed often have vaginal dryness. In some cases, this can lead to pain with sex, burning vaginal discomfort, itching and more. Vaginal Estrogen: An Option to be Considered for Postmenopausal Women Women's Healthcare Menopause Transition: Signs, Symptoms & Effects on the Body Editor's Picks: Vaginal Moisturizers To Treat Dryness Menopause Vaginal Changes Therapies for Vaginal Dryness Herstasis Health Foundation